Strobilurins F, G and H, three new antifungal metabolites from Bolinea lutea. I. Fermentation, isolation and biological activity.
نویسندگان
چکیده
Three new strobilurins F, G and H, antibiotics with antifungal activity, were isolated from cultures of Bolinea lutea Sacc. These new compounds differ from previously described analogs in their aromatic substitution. An HPLC method allows complete separation of all the components.
منابع مشابه
Strobilurins F, G and H, three new antifungal metabolites from Bolinea lutea. II. Structure determination.
To date six antifungal antibiotics of the strobilurin-type are known (Scheme 1): Strobilurin A (1)1>2) which is identical with mucidin3), strobilurin B (2)ia\ strobilurin C (3)4), methoxymucidin (4)5), hydroxystrobilurin D6) and strobilurin E7). They contain an unsaturated side chain with a terminal (£)-/?-methoxyaerylate moiety and differ usually in their aromatic substitution. In the precedin...
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ورودعنوان ژورنال:
- The Journal of antibiotics
دوره 43 6 شماره
صفحات -
تاریخ انتشار 1990